The Chicago Innovation Exchange is the University of Chicago’s hub for multidisciplinary collaborations. The CIE supports business start-up activities and entrepreneurs converting research and ideas into solutions benefitting society. The CIE Fab Lab includes 3D printers, CNC routers, a laser cutter, and vinyl cutter, a spray booth, and woodworking tools that are available to CIE members, partner institutions, and the community. We are planning outreach activities to connect Chicago's mid-south side and beyond to digital fabrication and scalable innovation.